Guy Karlebach
ASSISTANT PROFESSOR
Computer Science
School of Health and Natural Sciences
![Guy Karlebach from Computer Science](/sites/default/files/styles/facprofile_lg/public/media/images/2024-08/Guy%20Karlebach_2.jpg?h=97e68b80&itok=N4a75c7k)
gkarleba@fitchburgstate.edu
978.665.4635
Office: Edgerly Hall 312C
Website
Office Hours
Fall 2024
TBA
Courses Taught
Computer Science I (CSC 1500)
Data Communications/Networking (CSC 3400)
Computer and Network Security (CSC 4350)
Background
B.S. Computer Science - Technion - Israel Institute of Technology , Israel
M.S. Computer Science - Ben-Gurion University of the Negev, Israel
Ph.D. Computer Science - Tel Aviv University, Israel
I'm interested in computational aspects of inference and their application in Bioinformatics: Optimal inference of Boolean networks based on Kolmogorov Complexity, Bayesian modeling of large scale biological processes, in particular for resolving methodological issues associated with orthodox statistical approaches, optimization algorithms for complex problems of statistical inference and their application in Bioinformatics.
Betacoronavirus-specific alternate splicing, Karlebach et al. , Genomics Volume 114, Issue 2, March 2022
link: https://doi.org/10.1016/j.ygeno.2022.110270
link: https://doi.org/10.1016/j.ygeno.2022.110270
An expectation–maximization framework for comprehensive prediction of isoform-specific functions, Karlebach et al., Bioinformatics, Volume 39, Issue 4, April 2023 btad132
link: https://pubmed.ncbi.nlm.nih.gov/36929917/
link: https://pubmed.ncbi.nlm.nih.gov/36929917/
Computing Minimal Boolean Models of Gene Regulatory Networks, Karlebach and Robinson, Journal of Computational Biology, Volume 32 Number 2
link: https://engrxiv.org/preprint/view/2566
link: https://engrxiv.org/preprint/view/2566